(E/Z) -SIB-1893
SIB-1893 is a racemic mixture of its E and Z isomers. The (E) -isomer acts as a selective, noncompetitive antagonist of the metabotropic glutamate receptor 5 (mGluR5) . This activity underpins its use in research on neurological disorders, including studies of anticonvulsant mechanisms in experimental models.
Product Specifications
CAS Number
6266-99-5
Product Name Alternative
SIB1893, SIB-1893, SIB 1893, mGluR, (E/Z) -SIB 1893, (E/Z) -SIB1893, (E/Z) -SIB-1893
Field of Research
Neuroscience
Purity
99.92% (May vary between batches)
Solubility
DMSO:90 mg/mL (460.92 mM) ;10% DMSO+90% Saline:3.3 mg/mL (16.9 mM)
Smiles
C (=CC1=CC=CC=C1) C=2N=C (C) C=CC2
Molecular Formula
C14H13N
Molecular Weight
195.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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