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Sumatriptan

Sumatriptan (GR 43175 free base) is a selective 5-HT1B/1D/1F receptor agonist with oral bioavailability and blood-brain barrier penetration. It is widely used in research models of migraine and cerebrovascular function, employing both in vitro receptor binding assays and in vivo studies of neurogenic inflammation.

Product Specifications

CAS Number

103628-46-2

Product Name Alternative

Sumatriptan, 5HT Receptor, 5-HT1, 5HTReceptor, GR 43175 free base

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.77% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (11.17 mM) ; Ethanol:40 mg/mL (135.41 mM) ; DMSO:80 mg/mL (270.82 mM)

Smiles

O=S (=O) (NC) CC=1C=CC=2NC=C (C2C1) CCN (C) C

Molecular Formula

C14H21N3O2S

Molecular Weight

295.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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