What is the catalog number for KW-2449?

The catalog number for KW-2449 is orb1704022.

What sizes are available for KW-2449?

KW-2449 is available in the following size(s): 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does KW-2449 come in?

KW-2449 is available in 6 different pack sizes.

KW-2449 is currently made to order / not held in immediate stock. Contact us for lead time.

KW-2449

KW-2449 is a potent and selective small molecule inhibitor primarily targeting Flt3 (IC50 = 6.6 nM), with additional modest activity against Bcr-Abl, FGFR1, and Aurora A kinases. It has been utilized in preclinical research to investigate acute myeloid leukemia (AML) mechanisms and therapeutic strategies in both cellular and animal models.

Product Specifications

CAS Number

1000669-72-6

Product Name Alternative

Src, Abl, Abl (T315I), Apoptosis, AuroraKinase, Aurora A, Aurora Kinase, BcrAbl, Bcr-Abl, cKit, Cluster of differentiation antigen 135, CD135, JAK2, inhibit, KW 2449, KW2449, KW-2449, Kit, FLT3 (D835Y), FLT3, Fms like tyrosine kinase 3, FGFR, FGFR1, Fibroblast growth factor receptor, Inhibitor

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.43% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:55 mg/mL (165.46 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.02 mM) ; Ethanol:62 mg/mL (186.52 mM)