Z-FK-ck
Z-FK-ck (Z-Phe-Lys-2,4,6-Trimethylbenzoyloxy-methylketone) is a potent and selective gingipain-K-specific inhibitor. Z-FK-ck prolongs plasma thrombin time (TT) in a dose- and time-dependent manner[1].
Product Specifications
CAS Number
118253-05-7
Product Name Alternative
Z-Phe-Lys-2,4,6-Trimethylbenzoyloxy-methylketone
UNSPSC
12352209
Target
Cathepsin
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/z-fk-ck.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1=CC=CC=C1)N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCCN)C(COC(C3=C(C=C(C=C3C)C)C)=O)=O)=O
Molecular Formula
C34H41N3O6
Molecular Weight
587.71
References & Citations
[1]Imamura T, et, al. Effect of free and vesicle-bound cysteine proteinases of Porphyromonas gingivalis on plasma clot formation: implications for bleeding tendency at periodontitis sites. Infect Immun. 1995 Dec;63 (12) :4877-82.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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