UNC 0631
UNC 0631 is a potent and selective small-molecule inhibitor of the histone methyltransferase G9a (EHMT2), with an IC50 of 4 nM. It is widely used in epigenetic research to probe the role of H3K9 methylation in gene silencing, cancer biology, and cellular differentiation in both in vitro and in vivo models.
Product Specifications
CAS Number
1320288-19-4
Product Name Alternative
Chromatin, cell-penetration, inhibit, p53, KMT1D, Inhibitor, HistoneMethyltransferase, Histone Methyltransferase, EHMT1, G9a, H3K9me2, PKMT, UNC 0631, UNC0631, UNC-0631
Field of Research
Epigenetics & Chromatin
Purity
97.42% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.19 mM) ; Ethanol:5 mg/mL (7.86 mM) ; DMSO:49 mg/mL (77.05 mM)
Smiles
COc1cc2c (NC3CCN (CC4CCCCC4) CC3) nc (nc2cc1OCCCN1CCCCC1) N1CCCN (CC1) C (C) C
Molecular Formula
C37H61N7O2
Molecular Weight
635.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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