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YIL 781

YIL 781 is a potent and selective ghrelin receptor (GHS-R1a) antagonist with a Ki of 17 nM. It has been shown to improve glucose homeostasis in both in vivo and in vitro studies, primarily by inhibiting ghrelin-mediated pathways, making it a useful research tool for metabolic disorder investigations.

Product Specifications

CAS Number

875258-85-8

Product Name Alternative

YIL 781, YIL781, YIL-781, GHS-R1a

Field of Research

Pharmacology & Drug Discovery

Purity

98.80% (May vary between batches)

Solubility

H2O:40.1 mg/mL (97.92 mM) ; DMSO:40.1 mg/mL (97.92 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.88 mM)

Smiles

O=C1C=2C (N=C (C) N1C[C@@H]3CN (C (C) C) CCC3) =CC=C (OC4=CC=C (F) C=C4) C2

Molecular Formula

C24H28FN3O2

Molecular Weight

409.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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