ABC1183
ABC1183 is an orally bioavailable diaminothiazole inhibitor of GSK3α, GSK3β, and CDK9. It exhibits anti-proliferative activity in various cancer cell lines by inducing G2/M cell cycle arrest and modulating pathways involving β-catenin and MCL1, supporting its use in oncology research.
Product Specifications
CAS Number
1042735-18-1
Product Name Alternative
GSK3, GSK-3α, GSK-3β, ABC 1183, ABC1183, ABC-1183, CDK9/cyclin T1
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.53% (May vary between batches)
Solubility
DMSO:3.35 mg/mL (10.02 mM)
Smiles
Cc1ccc (Nc2nc (N) c (s2) C (=O) c2ccc (cc2) C#N) cc1
Molecular Formula
C18H14N4OS
Molecular Weight
334.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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