Afegostat HCl
Afegostat is a potent acid β-glucosidase (GCase) pharmacological chaperone, inhibiting both wild-type and mutant enzymes with nanomolar affinity (K (i) ~30 nM) . It has been investigated in preclinical research for Gaucher disease, including in vitro enzyme studies and in vivo animal models to assess its potential in stabilizing and enhancing mutant GCase activity.
Product Specifications
CAS Number
161302-93-8
Field of Research
Metabolism Research
Smiles
C (O) [C@@H]1[C@@H] (O) [C@H] (O) CNC1.Cl
Molecular Formula
C6H14ClNO3
Molecular Weight
183.63
Storage Conditions
-20°C
Notes
For research use only.
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