6-Methylnicotinamide

6-Methylnicotinamide is a nicotinamide derivative. 6-methylnicotinamide is also an endogenous metabolite and its sudden increase in the acute stages of intracerebral hemorrhage (ICH) exacerbates neurological damages in rat model. 6-Methylnicotinamide can significantly enhance the coordination effect between acylamino and undercoordinated defective Pb2+ cations. 6-Methylnicotinamide results in enhanced efficiency of perovskite solar cells to 24.33% with excellent environmental storage, heat, and light stabilities[1][2].

Product Specifications

CAS Number

[6960-22-1]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/6-methylnicotinamide.html

Purity

99.98

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC(C1=CN=C(C)C=C1)=O

Molecular Formula

C7H8N2O

Molecular Weight

136.15

Precautions

H315, H319, H335

References & Citations

[1]En Hu, et al. Temporal metabolomic alteration in rat brains of experimental intracerebral hemorrhage. Brain Res Bull. 2021 May;170:234-245.|[2]Lidan Liu, et al., Manipulating Electron Density Distribution of Nicotinamide Derivatives Toward Defect Passivation In Perovskite Solar Cells. Advanced energy materials, 2023.