Quoromycin

Quoromycin is a novel small molecule antivirulence agent that targets the quorum-sensing regulator SmcR in Vibrio vulnificus. By reducing SmcR's DNA-binding affinity, it effectively attenuates bacterial virulence, as demonstrated in both in vitro assays and in vivo infection models, making it a valuable research tool for studying bacterial pathogenesis and antivirulence strategies.