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EHT-6706

EHT-6706 is a potent colchicine-site tubulin polymerization inhibitor with broad-spectrum antiproliferative activity against drug-resistant tumor cell lines. It also functions as a vascular-disrupting agent, inhibiting angiogenesis in vitro by disrupting endothelial tube formation, migration, and monolayer integrity, as supported by transcriptomic analyses of antiangiogenic pathways.

Product Specifications

CAS Number

1351592-10-3

Smiles

C (C=1C2=C (C (N) =C (OCC) C=C2) C=NC1) C3=CC (OC) =C (OC) C (OC) =C3

Molecular Formula

C21H24N2O4

Molecular Weight

368.43

Storage Conditions

-20°C

Notes

For research use only.

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