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2-Iodomelatonin

2-Iodomelatonin is a high-affinity, MT1-selective melatonin receptor agonist (Ki = 28 pM; 5-fold MT1/MT2 selectivity) . It is extensively used as a radioligand in both in vitro and in vivo studies to map and characterize melatonin binding sites within central and peripheral nervous systems.

Product Specifications

CAS Number

93515-00-5

Product Name Alternative

2 Iodomelatonin, 2Iodomelatonin, 2-Iodomelatonin, Melatonin Receptor, MelatoninReceptor

Field of Research

Pharmacology & Drug Discovery

Purity

99.70% (May vary between batches)

Solubility

DMSO:55 mg/mL (153.56 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.58 mM)

Smiles

COc1ccc2[nH]c (I) c (CCNC (C) =O) c2c1

Molecular Formula

C13H15IN2O2

Molecular Weight

358.17

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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