ABT-546
ABT-546 (A-216546) is a potent and highly selective endothelin ETA receptor antagonist, exhibiting a Ki of 0.46 nM against the human ETA receptor. This small molecule is a valuable research tool for investigating the role of ET-1 signaling in cardiovascular and renal pathologies, applicable in both in vitro binding assays and in vivo disease models.
Product Specifications
CAS Number
212481-66-8
Field of Research
Pharmacology & Drug Discovery
Smiles
C (O) (=O) [C@@H]1[C@H] (CN (CC (N (CCCC) CCCC) =O) [C@H]1CC (CCC) (C) C) C=2C=C3C (=C (OC) C2) OCO3
Molecular Formula
C30H48N2O6
Molecular Weight
532.71
Storage Conditions
-20°C
Notes
For research use only.
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