BIO-32546
BIO-32546 (S-isomer) is a potent and selective autotaxin (ATX) inhibitor with a 1 nM IC50. This tool compound is widely used in vitro to study lysophosphatidic acid (LPA) signaling and has been utilized in vivo to investigate ATX's role in fibrosis, cancer, and inflammation.
Product Specifications
CAS Number
1548743-66-3
Product Name Alternative
Autotaxin (ATX), ATX (autotaxin), BIO32546, BIO-32546, BIO 32546
Field of Research
Metabolism Research
Purity
98.03% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.07 mM) ; DMSO:90 mg/mL (165.58 mM)
Smiles
C (F) (F) (F) C=1C2=C (C=CC1O[C@@H]3CC[C@H] (C (F) (F) F) CC3) C=CC ([C@H] (C) N4C5 (CC (C (O) =O) CC4 (CC5) [H]) [H]) =C2
Molecular Formula
C28H31F6NO3
Molecular Weight
543.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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