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C-Fms-IN-10

C-Fms-IN-10 is a potent and selective thieno[3,2-d]pyrimidine-based inhibitor of the CSF-1R (FMS) kinase, exhibiting an IC50 of 2 nM. This compound is a valuable research tool for studying tumor-associated macrophages and has demonstrated anti-tumor activity in both cellular assays and in vivo models.

Product Specifications

CAS Number

1527517-50-5

Field of Research

Signal Transduction

Smiles

Cc1nn (Cc2cccc (C) n2) c2cccc (NC (=O) c3csc4c (N) ncnc34) c12

Molecular Formula

C22H19N7OS

Molecular Weight

429.5

Storage Conditions

-20°C

Notes

For research use only.

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