CCR1 antagonist 7
CCR1 antagonist 7 (compound 16r) is a potent small molecule inhibitor of chemokine receptor 1, exhibiting an IC50 of 4 nM. This antagonist is a valuable research tool for studying CCR1-mediated pathways in inflammatory and autoimmune diseases, applicable in both in vitro binding assays and in vivo disease models.
Product Specifications
CAS Number
2446154-74-9
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
CC=1N (N=CC1C (N[C@@H] (CCC) C=2C=C (S (NC) (=O) =O) N=CC2) =O) C3=CC=C (Cl) C=C3
Molecular Formula
C21H24ClN5O3S
Molecular Weight
461.96
Storage Conditions
-20°C
Notes
For research use only.
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