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CCR1 antagonist 7

CCR1 antagonist 7 (compound 16r) is a potent small molecule inhibitor of chemokine receptor 1, exhibiting an IC50 of 4 nM. This antagonist is a valuable research tool for studying CCR1-mediated pathways in inflammatory and autoimmune diseases, applicable in both in vitro binding assays and in vivo disease models.

Product Specifications

CAS Number

2446154-74-9

Field of Research

Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery

Smiles

CC=1N (N=CC1C (N[C@@H] (CCC) C=2C=C (S (NC) (=O) =O) N=CC2) =O) C3=CC=C (Cl) C=C3

Molecular Formula

C21H24ClN5O3S

Molecular Weight

461.96

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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