EIF4A3-IN-1
EIF4A3-IN-1 is a potent and selective small molecule inhibitor of eukaryotic initiation factor 4A3 (eIF4A3), exhibiting an IC50 of 0.26 μM. This compound serves as a valuable chemical probe for studying the EJC and nonsense-mediated mRNA decay (NMD) pathways in both cellular and biochemical assays.
Product Specifications
CAS Number
2095486-67-0
Product Name Alternative
EIF4A3, eIF4A3 IN 1, eIF4A3IN1, eIF-4A3-IN-1, eIF4A3-IN-1, Eukaryotic Initiation Factor (eIF)
Field of Research
Cell Biology
Purity
99.49% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:5 mg/mL (8.49 mM) ; DMSO:160 mg/mL (271.7 mM)
Smiles
C (=O) (N1[C@H] (CN (C (=O) C2=C (C) N (N=C2) C3=CC (C#N) =CC=C3) CC1) C4=CC=C (Cl) C=C4) C5=CC=C (Br) C=C5
Molecular Formula
C29H23BrClN5O2
Molecular Weight
588.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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