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EIF4A3-IN-1

EIF4A3-IN-1 is a potent and selective small molecule inhibitor of eukaryotic initiation factor 4A3 (eIF4A3), exhibiting an IC50 of 0.26 μM. This compound serves as a valuable chemical probe for studying the EJC and nonsense-mediated mRNA decay (NMD) pathways in both cellular and biochemical assays.

Product Specifications

CAS Number

2095486-67-0

Product Name Alternative

EIF4A3, eIF4A3 IN 1, eIF4A3IN1, eIF-4A3-IN-1, eIF4A3-IN-1, Eukaryotic Initiation Factor (eIF)

Field of Research

Cell Biology

Purity

99.49% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:5 mg/mL (8.49 mM) ; DMSO:160 mg/mL (271.7 mM)

Smiles

C (=O) (N1[C@H] (CN (C (=O) C2=C (C) N (N=C2) C3=CC (C#N) =CC=C3) CC1) C4=CC=C (Cl) C=C4) C5=CC=C (Br) C=C5

Molecular Formula

C29H23BrClN5O2

Molecular Weight

588.88

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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