Estradiol 3-sulfamate
Estradiol 3-sulfamate (BLE 00084) is a potent, orally bioavailable inhibitor of estrone sulfatase (ES), exhibiting a K (i) of 73 nM in human placental microsomes. Its application is primarily in breast cancer research, where it is used to study ES inhibition in both in vitro enzymatic assays and in vivo models of hormone-dependent tumors.
Product Specifications
CAS Number
172377-52-5
Product Name Alternative
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
96.68% (May vary between batches)
Solubility
DMSO:50 mg/mL (142.26 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.69 mM)
Smiles
[H][C@@]12CC[C@H] (O) [C@@]1 (C) CC[C@]1 ([H]) c3ccc (OS (N) (=O) =O) cc3CC[C@@]21[H]
Molecular Formula
C18H25NO4S
Molecular Weight
351.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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