H89 · 2HCl
H-89 is a potent and selective protein kinase A (PKA) inhibitor with an IC50 of 48 nM. It is widely used in cardiovascular research, including studies of myocardial infarction and cardioprotection, and has been shown in rat models to affect spatial learning.
Product Specifications
CAS Number
127243-85-0
Product Name Alternative
PKA, protein kinase A, Protein kinase inhibitor H-89
Field of Research
Cell Biology, Signal Transduction
Purity
>98%
Bioactivity
PKA inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Water (up to 10 mg/ml) .
Smiles
O=S (=O) (NCCNCC=CC1=CC=C (Br) C=C1) C2=CC=CC=3C=NC=CC32
Molecular Formula
C20H20BrN3O2S·2HCl
Molecular Weight
519.28
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[2-[[3- (4-Bromophenyl) -2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride
Available Sizes
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