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Indirubin Derivative E804

E804, an indirubin derivative, is a potent and selective inhibitor of the insulin-like growth factor 1 receptor (IGF1R) . It demonstrates antitumor activity in vitro and has shown efficacy in reducing tumor growth in preclinical in vivo models, supporting its investigation in cancer research.

Product Specifications

CAS Number

854171-35-0

Product Name Alternative

Indirubin Derivative E804, Indirubin Derivative E-804, Indirubin Derivative E 804, IGF-1R, IGF1R

Field of Research

Signal Transduction

Purity

98.54% (May vary between batches)

Solubility

DMSO:100 mg/mL (273.69 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.95 mM)

Smiles

O=C1NC=2C=CC=CC2C1=C3NC=4C=CC=CC4C3=NOCCC (O) CO

Molecular Formula

C20H19N3O4

Molecular Weight

365.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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