PD-159020
PD-159020 is a dual endothelin receptor antagonist, inhibiting both human ETA and ETB receptors with IC50 values of 30 nM and 50 nM, respectively. This compound is a valuable research tool for investigating the role of endothelin signaling in cardiovascular diseases, pulmonary hypertension, and cancer in both cellular and animal models.
Product Specifications
CAS Number
177904-00-6
Field of Research
Pharmacology & Drug Discovery
Smiles
C (O) (=O) C1=C (C=2C (N1CC=3C=C4C (=CC3) OCO4) =CC (OCC5=CC=CC=C5) =C (OC) C2) C=6C=C7C (=CC6) OCO7
Molecular Formula
C32H25NO8
Molecular Weight
551.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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