PK68
PK68 is a potent and selective type II RIPK1 inhibitor (IC50 = 90 nM) . It is a valuable research tool for studying RIPK1-mediated pathways in inflammatory diseases and cancer metastasis, with utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2173556-69-7
Product Name Alternative
PK68, PK-68, PK 68, TNF, Receptor-interacting protein kinases, receptor-interacting kinase 1 (RIPK1), RIP kinase, RIPK, RIPK1, RIPkinase, type II inhibitor, oral, inflammatory, Inhibitor, inhibit, cancer
Field of Research
Cell Biology, Signal Transduction
Purity
98.09% (May vary between batches)
Solubility
DMSO:6.25 mg/mL (14.72 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.36 mM)
Smiles
CC (=O) Nc1nc2ccc (cc2s1) -c1cnc (C) c (NC (=O) OC2CCCCC2) c1
Molecular Formula
C22H24N4O3S
Molecular Weight
424.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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