RIP1 kinase inhibitor 1
This small molecule is a potent, orally bioavailable, and brain-penetrant RIP1 kinase inhibitor (pKi = 9.04) . It is a valuable research tool for investigating necroptosis and inflammation in both cellular assays and animal models of neurological and systemic diseases.
Product Specifications
CAS Number
2095515-38-9
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
CN1c2ccc (cc2OC[C@H] (N2CCc3c (Cl) n (Cc4ccccc4) nc3C2=O) C1=O) C#N
Molecular Formula
C24H20ClN5O3
Molecular Weight
461.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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