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RIP1 kinase inhibitor 1

This small molecule is a potent, orally bioavailable, and brain-penetrant RIP1 kinase inhibitor (pKi = 9.04) . It is a valuable research tool for investigating necroptosis and inflammation in both cellular assays and animal models of neurological and systemic diseases.

Product Specifications

CAS Number

2095515-38-9

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Smiles

CN1c2ccc (cc2OC[C@H] (N2CCc3c (Cl) n (Cc4ccccc4) nc3C2=O) C1=O) C#N

Molecular Formula

C24H20ClN5O3

Molecular Weight

461.9

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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