RORγt agonist 1
RORγt agonist 1 is a potent and orally bioavailable small molecule activator of the RORγt nuclear receptor, exhibiting an EC50 of 20.8 nM. It serves as a valuable research tool for investigating Th17 cell biology, autoimmune diseases, and cancer immunology in both cellular assays and animal models.
Product Specifications
CAS Number
2377378-89-5
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
S (=O) (=O) (N1C=2C (CC1CC (O) =O) =CC=C (C2) C3=CC (OC (F) F) =CC (F) =C3) C4=CC (C (F) (F) F) =CC=C4
Molecular Formula
C24H17F6NO5S
Molecular Weight
545.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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