Tariquidar methanesulfonate hydrate
Tariquidar methanesulfonate hydrate (XR9576) is a potent and selective inhibitor of the P-glycoprotein (P-gp) efflux pump. It is used in research to investigate P-gp function, particularly in overcoming multidrug resistance in cancer and modulating blood-brain barrier permeability in preclinical models.
Product Specifications
CAS Number
625375-83-9
Product Name Alternative
Pgp, P-gp, XR9576 methanesulfonate hydrate, XR 9576 methanesulfonate hydrate
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.13% (May vary between batches)
Solubility
H2O:4 mg/mL (4.22 mM) ; DMSO:200 mg/mL (211.18 mM)
Smiles
O=C (C1=CN=C2C=CC=CC2=C1) NC3=CC (OC) =C (C=C3C (NC4=CC=C (CCN5CC6=CC (OC) =C (C=C6CC5) OC) C=C4) =O) OC.O=S (O) (C) =O.O=S (O) (C) =O.O.O.O.O.O.O
Molecular Formula
C40H58N4O18S2
Molecular Weight
947.04
Storage Conditions
-20°C
Notes
For research use only.
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