TrkA-IN-1
TrkA-IN-1 is a potent, cell-active, and selective inhibitor of Tropomyosin-related kinase A (TrkA), demonstrating an IC50 of 99 nM. This compound serves as a valuable research tool for investigating TrkA signaling in pain pathways and has shown analgesic efficacy in preclinical in vivo models.
Product Specifications
CAS Number
1680179-43-4
Field of Research
Signal Transduction
Smiles
Cc1ncc (NC (=O) NC2c3ccccc3-c3ccccc23) c (n1) -c1ccccc1
Molecular Formula
C25H20N4O
Molecular Weight
392.45
Storage Conditions
-20°C
Notes
For research use only.
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