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Cloperastine fendizoate

Cloperastine fendizoate (Hustazol) is a potent, concentration-dependent inhibitor of the hERG potassium channel, with an IC50 of 27 nM. This property makes it a valuable pharmacological tool for in vitro cardiac safety research and studies of long QT syndrome mechanisms.

Product Specifications

CAS Number

85187-37-7

Product Name Alternative

Cloperastine fendizoate, hERG Potassium Channel, Hustazol, K+ currents

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.85% (May vary between batches)

Solubility

DMSO:8 mg/mL (12.34 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.54 mM)

Smiles

Clc1ccc (cc1) C (OCCN1CCCCC1) c1ccccc1.OC (=O) c1ccccc1C (=O) c1ccc (O) c (c1) -c1ccccc1

Molecular Formula

C40H38ClNO5

Molecular Weight

648.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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