EC0489
EC0489 is a folate receptor (FR) -targeting small molecule-drug conjugate (SMDC) composed of folic acid linked to desacetyl vinblastine hydrazide. It is a research tool for studying targeted drug delivery in models of refractory or metastatic FR-positive cancers, applicable in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
1096702-14-5
Field of Research
Cell Biology
Smiles
[H][C@@]12N3CC[C@@]11c4cc (c (OC) cc4N (C) [C@@]1 ([H]) [C@] (O) ([C@H] (O) [C@]2 (CC) C=CC3) C (=O) NNC (=O) OCCSSC[C@H] (NC (=O) [C@H] (CCC (=O) NC[C@H] (O) [C@@H] (O) [C@H] (O) [C@H] (O) CO) NC (=O) [C@H] (CCC (O) =O) NC (=O) [C@H] (CCC (=O) NC[C@H] (O) [C@@H] (O) [C@H] (O) [C@H] (O) CO) NC (=O) [C@H] (CCC (O) =O) NC (=O) [C@H] (CCC (=O) NC[C@H] (O) [C@@H] (O) [C@H] (O) [C@H] (O) CO) NC (=O) CC[C@H] (NC (=O) c1ccc (NCc2c[nH]c3nc (N) nc (=O) c3n2) cc1) C (O) =O) C (O) =O) [C@]1 (C[C@@]2 ([H]) C[N@] (C[C@] (O) (CC) C2) CCc2c1[nH]c1ccccc21) C (=O) OC |c:29|
Molecular Formula
C111H156N22O43S2
Molecular Weight
2550.7
Storage Conditions
-20°C
Notes
For research use only.
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