Apratastat
Apratastat is a potent, orally bioavailable dual inhibitor of TACE and MMPs, effectively suppressing TNF-α release. It demonstrates significant activity in vitro, ex vivo, and in vivo models, making it a valuable research tool for studying inflammatory and autoimmune diseases, cancer, and tissue remodeling processes.
Product Specifications
CAS Number
287405-51-0
Field of Research
Cell Biology, Protein Biochemistry
Smiles
CC1 (C) SCCN ([C@H]1C (=O) NO) S (=O) (=O) c1ccc (OCC#CCO) cc1
Molecular Formula
C17H22N2O6S2
Molecular Weight
414.5
Storage Conditions
-20°C
Notes
For research use only.
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