BRD5529
BRD5529 is a selective small molecule inhibitor that disrupts the CARD9-TRIM62 protein-protein interaction (IC50 = 8.6 μM) . It blocks TRIM62-mediated ubiquitination and subsequent activation of CARD9, serving as a useful tool for studying CARD9 signaling in innate immunity and inflammation research, both in vitro and in vivo.
Product Specifications
CAS Number
1358488-78-4
Field of Research
Protein Biochemistry
Smiles
Cc1ccc (cc1) C (=O) Nc1cnc (N2CCC (CC2) (N2CCCCC2) C (N) =O) c (c1) C (O) =O
Molecular Formula
C25H31N5O4
Molecular Weight
465.54
Storage Conditions
-20°C
Notes
For research use only.
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