B I09
B I09 is an IRE-1 RNase inhibitor (IC50 = 1230 nM) that blocks XBP1 mRNA splicing in vitro in human WaC3 cells and suppresses xbp-1 expression in LPS-stimulated B cells. This compound is a useful research tool for modeling XBP-1 deficiency in chronic lymphocytic leukemia (CLL) cell studies.
Product Specifications
CAS Number
1607803-67-7
Product Name Alternative
IRE-1 RNase, IRE1 Rnase, B I09, B I-09
Field of Research
Cell Biology
Purity
98.80% (May vary between batches)
Solubility
10% DMSO+90% Saline:1 mg/mL (3.3 mM) ; DMSO:11 mg/mL (36.27 mM)
Smiles
Oc1ccc2c3CCNCc3c (=O) oc2c1C1OCCCO1
Molecular Formula
C16H17NO5
Molecular Weight
303.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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