B I09
B I09 is an IRE-1 RNase inhibitor (IC50 = 1230 nM) that blocks XBP1 mRNA splicing in vitro in human WaC3 cells and suppresses xbp-1 expression in LPS-stimulated B cells. This compound is a useful research tool for modeling XBP-1 deficiency in chronic lymphocytic leukemia (CLL) cell studies.
Product Specifications
CAS Number
1607803-67-7
Product Name Alternative
IRE-1 RNase, IRE1 Rnase, B I09, B I-09
Field of Research
Cell Biology
Purity
98.80% (May vary between batches)
Solubility
10% DMSO+90% Saline:1 mg/mL (3.3 mM) ; DMSO:11 mg/mL (36.27 mM)
Smiles
Oc1ccc2c3CCNCc3c (=O) oc2c1C1OCCCO1
Molecular Formula
C16H17NO5
Molecular Weight
303.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K3896203 1.0 µg DNA
Cadps2 sgRNA CRISPR Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details 