Momelotinib Mesylate
Momelotinib Mesylate is a potent and selective small molecule inhibitor targeting JAK1 and JAK2 kinases, exhibiting approximately 10-fold lower activity against JAK3. It has been utilized in research models of myelofibrosis and anemia to investigate its effects on cytokine signaling, splenomegaly, and hepcidin modulation in both cellular and animal studies.
Product Specifications
CAS Number
1056636-07-7
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
CS (O) (=O) =O.O=C (NCC#N) c1ccc (cc1) -c1ccnc (Nc2ccc (cc2) N2CCOCC2) n1
Molecular Formula
C24H26N6O5S
Molecular Weight
510.57
Storage Conditions
-20°C
Notes
For research use only.
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