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Elobixibat

Elobixibat (A 3309) is a potent and selective ileal bile acid transporter (IBAT) inhibitor with IC50 values of 0.13 nM (mouse), 0.53 nM (human), and 5.8 nM (canine) . This investigational compound is utilized in preclinical and clinical research for studying chronic idiopathic constipation and related gastrointestinal motility disorders.

Product Specifications

CAS Number

439087-18-0

Product Name Alternative

Mouse IBAT, Elobixibat, IBAT, human IBAT, A 3309, A3309, A-3309, AZD 7806, AZD7806, AZD-7806, canine IBAT

Field of Research

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Purity

97.43% (May vary between batches)

Solubility

DMSO:225 mg/mL (323.33 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.19 mM)

Smiles

CCCCC1 (CCCC) CN (c2ccccc2) c2cc (SC) c (OCC (=O) N[C@@H] (C (=O) NCC (O) =O) c3ccccc3) cc2S (=O) (=O) C1

Molecular Formula

C36H45N3O7S2

Molecular Weight

695.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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