SAFit2
SAFit2 is a potent and selective FKBP51 inhibitor (Ki = 6 nM) that modulates the AKT2-AS160 pathway and glucocorticoid signaling. It is a research tool for studying metabolic disorders, neuropsychiatric conditions, and chronic pain in preclinical models.
Product Specifications
CAS Number
1643125-33-0
Product Name Alternative
FKBP51, SAFit2, SAFit-2
Field of Research
Cell Biology, Immunology & Inflammation
Purity
98.16% (May vary between batches)
Solubility
DMSO:87.5 mg/mL (108.97 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.11 mM)
Smiles
COc1ccc (CC[C@@H] (OC (=O) [C@@H]2CCCCN2C (=O) [C@@H] (C2CCCCC2) c2cc (OC) c (OC) c (OC) c2) c2cccc (OCCN3CCOCC3) c2) cc1OC
Molecular Formula
C46H62N2O10
Molecular Weight
802.99
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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