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Silvestrol

Silvestrol is a potent and selective inhibitor of eukaryotic initiation factor 4A (eIF4A), disrupting cap-dependent translation. This activity induces both autophagy and caspase-dependent apoptosis, making it a valuable tool for studying oncology, translational control, and cell death mechanisms in vitro and in vivo cancer models.

Product Specifications

CAS Number

697235-38-4

Field of Research

Cell Biology

Smiles

CO[C@@H]1OC[C@@H] (O[C@H]1Oc1cc2O[C@]3 ([C@@H] ([C@H] ([C@@H] (O) [C@@]3 (O) c2c (OC) c1) C (=O) OC) c1ccccc1) c1ccc (OC) cc1) [C@H] (O) CO

Molecular Formula

C34H38O13

Molecular Weight

654.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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