Silvestrol
Silvestrol is a potent and selective inhibitor of eukaryotic initiation factor 4A (eIF4A), disrupting cap-dependent translation. This activity induces both autophagy and caspase-dependent apoptosis, making it a valuable tool for studying oncology, translational control, and cell death mechanisms in vitro and in vivo cancer models.
Product Specifications
CAS Number
697235-38-4
Field of Research
Cell Biology
Smiles
CO[C@@H]1OC[C@@H] (O[C@H]1Oc1cc2O[C@]3 ([C@@H] ([C@H] ([C@@H] (O) [C@@]3 (O) c2c (OC) c1) C (=O) OC) c1ccccc1) c1ccc (OC) cc1) [C@H] (O) CO
Molecular Formula
C34H38O13
Molecular Weight
654.66
Storage Conditions
-20°C
Notes
For research use only.
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