SPR inhibitor 3
SPR inhibitor 3 is a potent small molecule targeting sepiapterin reductase (SPR), effectively reducing tetrahydrobiopterin (BH4) levels. It demonstrates high in vitro affinity (IC50=74 nM) and cellular activity (IC50=5.2 μM), underpinning its utility in researching neuropathic and inflammatory pain mechanisms in both cellular and animal models.
Product Specifications
CAS Number
1292285-54-1
Field of Research
Metabolism Research, Metabolism Research; Pharmacology & Drug Discovery
Smiles
O=C (NCCC=1C=2C=C (O) C=CC2NC1C) COC
Molecular Formula
C14H18N2O3
Molecular Weight
262.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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