VZ185
VZ185 is a potent and selective PROTAC molecule that effectively degrades BRD9 and BRD7 with DC50 values of 1.8 nM and 4.5 nM, respectively. This degrader is a valuable chemical probe for studying bromodomain function in cancer biology and epigenetics research, both in cellular and in vivo models.
Product Specifications
CAS Number
2306193-61-1
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
99.98% (May vary between batches)
Smiles
CN1C=C (C=2C (C1=O) =CN=CC2) C3=CC (OC) =C (CN4CCN (CCCCCOC5=C (CNC (=O) [C@H]6N (C ([C@@H] (NC (=O) C7 (F) CC7) C (C) (C) C) =O) C[C@H] (O) C6) C=CC (=C5) C=8SC=NC8C) CC4) C (OC) =C3
Molecular Formula
C53H67FN8O8S
Molecular Weight
995.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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