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Troleandomycin

Troleandomycin, an orally bioavailable macrolide antibiotic, acts as a selective CYP3A inhibitor. It is utilized in pharmacological research for studying drug metabolism, enzyme interactions, and steroid-sparing effects in asthma models. Its application extends to investigating mechanisms of drug-induced cholestasis in both in vitro and in vivo systems.

Product Specifications

CAS Number

2751-09-9

Product Name Alternative

Triacetyl Oleandomycin; TAO; NSC-108166

Field of Research

Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery

Purity

>98%

Bioactivity

Macrolide antibiotic, Inhibits cytochrome P450

Form

Powder

Solubility

Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml) .

Smiles

[H][C@@]1 (C[C@H] (OC) [C@@H] (OC (C) =O) [C@H] (C) O1) O[C@H]1[C@H] (C) [C@@H] (O[C@]2 ([H]) O[C@H] (C) C[C@@H] ([C@H]2OC (C) =O) N (C) C) [C@@H] (C) C[C@@]2 (CO2) C (=O) [C@H] (C) [C@@] ([H]) (OC (C) =O) [C@@H] (C) [C@@H] (C) OC (=O) [C@@H]1C

Molecular Formula

C41H67NO15

Molecular Weight

814.0

Storage Conditions

RT

Notes

For research use only.

Other Product Names

Oleandomycin,2”,4’,11-triacetate

Available Sizes

Frequently Asked Questions

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