IRAK4-IN-4
IRAK4-IN-4 (Compound 15) is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, with an IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM. IRAK4-IN-4 can be used for research of autoimmune diseases[1].
Product Specifications
CAS Number
1850276-58-2
Product Name Alternative
Hydroxypropyl Cellulose, Viscosity(5%):75-150mPa.s, MW 100000,Hydroxypropyl Cellulose, Viscosity(1%):1275-3500mPa.s,Hydroxypropyl Cellulose, Viscosity(2%):95000-105000mPa.s,BafA1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cyclic GMP-AMP Synthase; IRAK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/irak4-in-4-1.html
Concentration
10mM
Purity
99.55
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C2=CC=CC=C2)N=C3C=C(C)C=CN31)C(C4=CC=CC=C4)=O
Molecular Formula
C22H16N2O2
Molecular Weight
340.37
Precautions
H302, H315, H319, H335
References & Citations
[1]One class has the naphthalene second dione compounds and its derivative of protease modification activities. CN107163044A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IRAK4
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Cytochrome P450 26B (CYP26B1) (418-430) Goat Polyclonal Antibody
ALS2CR1 (NIF3L1) (NM_001142355) Human Over-expression Lysate
