CA 074
CA 074 is a highly potent and selective cathepsin B inhibitor (Ki = 2-5 nM) . It has demonstrated neuroprotective effects in primate models of ischemic neuronal death and attenuates neuroinflammatory pathologies like retinopathy and optic neuritis in murine EAE models, supporting its use in neuroscience and immunology research.
Product Specifications
CAS Number
134448-10-5
Product Name Alternative
CA 074, CA074, CA-074, Cathepsin B, Cysteine Protease, CysteineProtease
Field of Research
Protein Biochemistry
Purity
97.80% (May vary between batches)
Solubility
DMSO:100 mg/mL (260.8 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.43 mM)
Smiles
[H][C@] (NC (=O) [C@H]1O[C@@H]1C (=O) NCCC) ([C@@H] (C) CC) C (=O) N1CCC[C@H]1C (O) =O
Molecular Formula
C18H29N3O6
Molecular Weight
383.44
Storage Conditions
-20°C
Notes
For research use only.
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