Aliskiren
Aliskiren (CGP 60536) is a potent, orally bioavailable renin inhibitor with an IC50 of 1.5 nM. It is widely used in cardiovascular research to study hypertension mechanisms, employing both in vitro enzymatic assays and in vivo animal models of blood pressure regulation.
Product Specifications
CAS Number
173334-57-1
Product Name Alternative
CGP60536B, CGP 60536, Aliskiren, SPP 100, renin
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
97.02% (May vary between batches)
Solubility
DMSO:80 mg/mL (144.99 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.98 mM) ; Ethanol:80 mg/mL (144.99 mM)
Smiles
COCCCOc1cc (C[C@@H] (C[C@H] (N) [C@@H] (O) C[C@@H] (C (C) C) C (=O) NCC (C) (C) C (N) =O) C (C) C) ccc1OC
Molecular Formula
C30H53N3O6
Molecular Weight
551.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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