AD57
AD57 is a potent dual inhibitor of c-Src and Abl kinases, exhibiting IC50 values of 25 nM and 41 nM, respectively. This small molecule is a valuable research tool for studying oncogenic signaling in vitro and has been utilized in cellular models of cancer proliferation and metastasis.
Product Specifications
CAS Number
1093380-42-7
Product Name Alternative
Abl, AD 57, AD57, AD-57, BcrAbl, c-Src
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.23% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.39 mM) ; DMSO:55 mg/mL (120.76 mM)
Smiles
CC (C) n1nc (-c2ccc (NC (=O) Nc3cccc (c3) C (F) (F) F) cc2) c2c (N) ncnc12
Molecular Formula
C22H20F3N7O
Molecular Weight
455.44
Storage Conditions
-20°C
Notes
For research use only.
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