LY 272015 hydrochloride
LY 272015 hydrochloride is a potent and selective 5-HT2B receptor antagonist for research use. It demonstrates oral activity, inhibiting serotonin-mediated ERK2 phosphorylation and cellular responses in vitro, and shows antihypertensive effects in DOCA-salt hypertensive rat models in vivo, supporting its utility in cardiovascular and oncology research.
Product Specifications
CAS Number
172895-15-7
Product Name Alternative
LY272015 Hydrochloride, LY-272015 Hydrochloride, 5HTReceptor, 5HT Receptor, 5-HT2B
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.47% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble.) ; DMSO:2 mg/mL (5.36 mM)
Smiles
Cl.O (C1=CC=C (C=C1OC) CC2NCCC=3C=4C=C (C=CC4NC32) C) C
Molecular Formula
C21H25ClN2O2
Molecular Weight
372.89
Storage Conditions
-20°C
Notes
For research use only.
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