NSC33994
NSC 33994 is a potent and selective JAK2 inhibitor with an IC50 of 60 nM, demonstrating no activity against Src or TYK2 at 25 μM. This small molecule is a valuable research tool for studying JAK-STAT signaling in hematological malignancies and inflammatory diseases in both cellular and animal models.
Product Specifications
CAS Number
82058-16-0
Product Name Alternative
G6
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
JAK2 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 2 mg/ml with warming) or in Ethanol (up to 4 mg/ml with warming) .
Smiles
CCN (CC) Cc1cc (ccc1O) C (\CC) =C (/CC) c1ccc (O) c (CN (CC) CC) c1
Molecular Formula
C28H42N2O2
Molecular Weight
436.65
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
E-4,4’- (1,2-Diethyl-1,2-ethenediyl) bis[2-[ (diethylamino) methyl]phenol
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