Ro 32-0432 hydrochloride
Ro 32-0432 is an orally bioavailable, ATP-competitive pan-PKC inhibitor targeting isoforms including α, βI, βII, γ, and ε. It suppresses T-cell activation, supporting research in immune and inflammatory diseases. The (S) -enantiomer hydrochloride also acts as a GRK5 inhibitor and has shown efficacy in preclinical models of nicotine withdrawal.
Product Specifications
CAS Number
151342-35-7
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1C (C2=C3N (C=4C2=CC=CC4) CC[C@H] (CN (C) C) C3) =C (C (=O) N1) C=5C=6C (N (C) C5) =CC=CC6
Molecular Formula
C28H28N4O2
Molecular Weight
452.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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